This book constitutes the refereed proceedings of the 12th European Conference on Artificial Intelligence in Music, Sound, Art and Design, EvoMUSART 2023, held as part of Evo 2023, in April 2023, co-located with the Evo 2023 events, EvoCOP, EvoApplications, and EuroGP. The 20 full papers and 7 short papers presented in this book were carefully reviewed and selected from 55 submissions. They cover a wide range of topics and application areas of artificial intelligence, including generative approaches to music and visual art, deep learning, and architecture.