This volume consists of twenty peer-reviewed papers from the special session on pseudodifferential operators and the special session on generalized functions and asymptotics at the Eighth Congress of ISAAC held at the Peoples¿ Friendship University of Russia in Moscow on August 22¿27, 2011. The category of papers on pseudo-differential operators contains such topics as elliptic operators assigned to diffeomorphisms of smooth manifolds, analysis on singular manifolds with edges, heat kernels and Green functions of sub- Laplacians on the Heisenberg group and Lie groups with more complexities than but closely related to the Heisenberg group, Lp-boundedness of pseudo- differential operators on the torus, and pseudo-differential operators related