Recognition Receptors in Biosensors
- Springer New York
- 2016
- Taschenbuch
- 880 Seiten
- ISBN 9781493939404
Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli- exclusion-principle-derived inter-atomic repulsion, and a strong, ¿attractive¿ force arising largely
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