Abhirup Datta / Priti Kumar Roy
Mathematical Models for Therapeutic Approaches to Control Psoriasis
- Springer Nature Singapore
- 2019
- Taschenbuch
- 108 Seiten
- ISBN 9789811390197
This book discusses several mathematical models highlighting the disease dynamics of psoriasis and its control. It explains the control of keratinocyte concentration through a negative feedback mechanism and the effect of including a realistic time delay in that system. The effect of cytokine release is described in a mathematical model of psoriasis and further elucidated in two different mathematical pathways: the ordinary differential equation model system, and the fractional-order differential equation model system. The book also identifies the role of CD8+ T-cells in psoriasis by investigating the interaction between dendritic cells and CD8+ T-cells. Presenting an approach to control the fractional-order system to prevent excess production
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