![Ribatti, Domenico. The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis - The CAM assay in the study of angiogenesis and metastasis. Springer Netherlands, 2014.](https://eichendorff21.de/cdata/u3qV34b83BIqieGrDuCwlyiXzn8=/300x0/9789400791572.png)
Domenico Ribatti
The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis
- Springer Netherlands
- 2014
- Taschenbuch
- 136 Seiten
- ISBN 9789400791572
As pointed out by Auerbach in 1991 ¿Perhaps the most consistent limitation to progress in angiogenesis research has been the availability of simple, reliable, reproducible, quantitative assays of the angiogenesis response.¿ In vitro angiogenesis assays, based on endothelial cell cultures or tissue explant, focus on isolated endothelial cell functions (e.g., endothelial cell proliferation, migration, or invasion) and do not examine the coordination of cell functions required for a successful angiogenic response (Jain et al., 1997; Auerbach et al., 2000). Although in vitro angiogenesis assays have been useful for identi cation of potential molecular targets to block endothelial cell responses and preliminary screening of novel pharmacological agents,
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