Biological cell membranes regulate the transfer of matter and informa­ tion between the intracellular and extracellular compartments as basic survival and maintenance functions for an organism: This volume contains a series of reviews that are concerned with how biological plasma membranes regulate the transport of chloride between the intracellular and extracellular compartments of a cell. This book is also an attempt to analyze the molecular basis for the movement of chloride across a cell membrane. This volume is devoted to a diversity of electrogenic chloride transport mechanisms in representative cell membranes of all living things. The first section of the book (Chaps. 1-4) focuses on mech­