This book presents the results of the GMLS II conference on «Implications of GM-Crop Cultivation at Large Spatial Scales», held in Bremen in March 2010. The meeting was a platform to discuss ecological, agricultural and economic implications of genetically modified organisms (GMO) and to present new developments in risk assessment and monitoring. Approaches in co-existence regulations and nature protection standards are presented as well as legal challenges and resolutions on national and on EU-level. The book collects 30 contributions written by specialists in science, administration and jurisprudence from Europe as well as Africa, Central America, and Russia.