This book provides a selection of reports and survey articles on the latest research in the area of single and multivariable operator theory and related fields. The latter include singular integral equations, ordinary and partial differential equations, complex analysis, numerical linear algebra, and real algebraic geometry - all of which were among the topics presented at the 26th International Workshop in Operator Theory and its Applications, held in Tbilisi, Georgia, in the summer of 2015. Moreover, the volume includes three special commemorative articles. One of them is dedicated to the memory of Leiba Rodman, another to Murray Marshall, and a third to Boris Khvedelidze, an outstanding