This book addresses the science of artificial and design theory in the context of the scientific research development environment. The author discusses the concepts, activities and techniques associated with the emerging methodology Design Science Research (DSR). Further, he examines the main challenges for its implementation, based on an analysis of the DSR literature, variations of DSR (i.e. Action Design Research, and Grounded Design), and the applicability of DSR in various disciplines related to innovation, both within and outside of the professional school. As a result, this book goes beyond conceptual issues of DSR, presenting and discussing more pragmatic issues and challenges faced by researchers. Design Science