The International Conference on Complex Systems (ICCS) offers a unique interdisciplinary venue for researchers from the physical and biological sciences, social sciences, psychology and cognitive science, engineering, medicine, human systems, and global systems. This proceedings volume gathers selected papers from the conference. The New England Complex Systems Institute (NECSI) has been instrumental in the development of complex systems science and its applications. NECSI pursues research, education, knowledge dissemination, and community development efforts around the world to promote the study of complex systems and its application for the benefit of society. NECSI hosts the International Conference on Complex Systems and publishes the NECSI Book.