This book constitutes the refereed proceedings of the 32nd International Conference on Advanced Information Systems Engineering, CAiSE 2020, held in Grenoble, France, in June 2020. The 33 full papers presented in this volume were carefully reviewed and selected from 185 submissions. The book also contains one invited talk in full paper length. The papers were organized in topical sections named: distributed applications; AI and big data in IS; process mining and analysis; requirements and modeling; and information systems engineering. Abstracts on the CAiSE 2020 tutorials can be found in the back matter of the volume. The conference was held virtually due to the COVID-19 pandemic.