This volume LNCS 11877 constitutes the refereed proceedings of the Confederated International Conferences: Cooperative Information Systems, CoopIS 2019, Ontologies, Databases, and Applications of Semantics, ODBASE 2019, and Cloud and Trusted Computing, C&TC;, held as part of OTM 2019 in October 2019 in Rhodes, Greece. The 38 full papers presented together with 8 short papers were carefully reviewed and selected from 156 submissions. The OTM program every year covers data and Web semantics, distributed objects, Web services, databases, information systems, enterprise workflow and collaboration, ubiquity, interoperability, mobility, grid and high-performance computing.