Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine. In this latest volume, parts one and two discuss recent developments in male and female infertility respectively, including fertility preservation in the male adolescent cancer patient, the clinical relevance of sperm RNA, the management of subclinical hypothyroidism, and the effects of endocrine-disrupting chemicals. Part three covers the latest in ART, such as evidence-based morphological approaches for embryo selection and culturing human embryos. The final section highlights controversies in