Dr Perlmutter's #1 New York Times bestseller about the devastating effects of gluten, sugar and carbs on the brain and body - updated with the latest nutritional and neurological science. When Grain Brain was published in 2013, Dr Perlmutter kickstarted a revolution. Since then, his book has been translated into 30 languages, and more than 1.5 million readers have been given the tools to make monumental life-changing improvements to their health. They've lost weight, banished anxiety and depression, reduced or eliminated chronic conditions, and taken proactive steps to safeguard themselves against cognitive decline and neurological disease - all without drugs. In this fully revised, 5-year anniversary edition, Dr Perlmutter builds on his mission. Drawing on the latest developments in scientific research, he explains how the Grain Brain programme boosts the brain, shows the benefits of using fat as a main fuel source, and puts forth the most compelling evidence to date that a non-GMO, gluten-free and low-carb diet is crucial for cognitive function and long-term health. Featuring the latest data and practical advice based on cutting-edge