of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: * Detailed chapters on the type of trial designs, such as adaptive, crossover, group- randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials * Over 100 contributions from leading academics, researchers, and practitioners * An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to- child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.