regulating the endothelium and smooth muscle cells,in?ammatory cells, mediators, airway surface liquid, and pharmacological therapy that focuses on how in?amed airways are altered. Written primarily for predoctoral and postdoctoral graduates in the basic medical sciences, the medical student and postdoctoral physician, graduates in the allied s- ences, nurses, pulmonologists, and physicians in critical care medicine, this book p- vides many of the fundamentals of contemporary pulmonology. It is divided into several parts devoted to the control of respiration, arterial chemoreceptors,muscles of ventilation, pulmonary physiology, and gas exchange in health, exercise, and disease. Special emphasis is placed on emphysema and its pathobiology, acute lung injury, asthma and inhaled toxicants. Because the ?eld is always evolving, each chapter includes recommended readings that lead the reader to sources of additional information, such as the review on remodeling of the blood gas barrier by West and Mathieu-Costello.